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Slow Down Estrogen Decline
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4.8* 784 Reviews | 273+ Clinician Shares

Estrogen Support Probiotic

Oval uses a clinically-studied probiotic blend to support hormone balance—so you can get your old self back.

Regulates hormones through the gut microbiome

Relieves symptoms of perimenopause and menopause

Balances estrogen, progesterone and cortisol levels

Improves mood, irritability and trouble sleeping

Helps maintain a healthy weight and reduce bloating

Clinically studied in gold-standard trials

Exclusive Welcome Offer
Exclusive Welcome Offer
$79.99
$29.99

Your gut may be affecting your hormones more than you think. New customers try it at 63% off.

Select Your Plan

NEW CUSTOMERS: LIMITED TIME OFFER

Monthly
63% OFF
$79.99
$29.99
/mo
30 servings | Cancel anytime
$0.99 /day
Glass storage and travel jar with every subscription
Ongoing orders renew at the standard 25% discount rate
One Time Purchase
$79.99
30 servings | Delivered once
$2.66 /day
Delivery by Wed 27th May 

90-day money back guarantee

Free shipping on all orders

Pause or cancel anytime

Product Information

How We Compare

Traditional Supplements
Hormone Therapy
Supports Estrogen Levels
Proven Symptom Relief
Clinically Studied Results
Doctor Recommended
Third-Party Tested
No Prescription Needed
Non-Hormonal

Vegan

Gluten-Free

Non-GMO

No Added Hormones

Clinically-Backed

Third-Party Tested

Estrogen is a key hormone for women's health. Every single part of a woman's body depends on estrogen to operate at its best—including the brain, bones, heart, and muscles.

ALICIA JACKSON, Ph.D.
FDA ANNOUNCEMENT, NOVEMBER 2025

Estrogen regulates insulin sensitivity and fat distribution, helping to reduce midsection weight gain and improve metabolism.

By boosting collagen and follicle health, estrogen keeps skin firm and glowing while promoting thicker, shinier hair.

Estrogen fuels neurotransmitters that improve memory, reduce brain fog and increase control over mood swings.

Estrogen helps regulate your internal clock and stabilize nighttime temperature, supporting deeper, more restorative sleep.

Estrogen supports vaginal tissue health and natural lubrication, supporting comfort and sex drive through midlife.

Estrogen maintains bone density and supports healthy joints, reducing the risk of osteoporosis and improving mobility as you age.

Estrogen maintains healthy cholestrerol ratios and blood vessel elasticity, promoting cardiovascular function.

Feel Like Yourself Again

4.8 stars

My midsection feels less puffy and my digestion finally feels regular again.

– Tanya R, 51

My cravings aren’t running the show anymore. I feel more in control.

– Melissa K, 44

I feel lighter and more balanced overall, like my body’s working with me again.

– Daphne W, 53

I fall asleep easier and stay asleep more consistently—it’s a huge relief.

– Paige M, 44

I just feel calmer in the evenings, not wired like before.

– Hannah B, 48

My sleep feels deeper and I wake up more centered.

– Jade F, 52

The brain fog lifted. I feel clearer and more myself again.

– Lauren E, 51

My mood feels steadier, not up and down all day.

– Kelly A, 48

I’m more focused and organized, even during stressful weeks.

– Clara H, 43

No more afternoon crash—my energy actually lasts.

– Erin H, 55

My energy feels clean and steady, not jittery.

– Monica R, 43

I finally have the motivation to move my body again.

– Talia F, 45

My skin feels more hydrated and calm than it has in years.

– Rachel S, 49

People keep commenting on my glow—especially when I’m not wearing makeup.

– Nora D, 55

My complexion looks smoother and more even-toned.

– Jo B, 42

More comfort, less dryness, and I feel more like myself again.

– Tess M, 45

I’m reconnecting with my body in a way I wasn’t expecting.

– Anna D, 43

Intimacy feels easier and more natural now.

– Lara V, 56

How Oval Works

How Oval Works

1.

Produces a natural enzyme

Probiotic strains in Oval make beta-glucuronidase, which helps unlock estrogen stored in your gut.

2.

Sustains estrogen levels

Once unlocked, this estrogen can be naturally reused by your body to sustain healthy levels.

3.

Feel like yourself again

Estrogen supports the systems that make you feel like you—your mood, energy, and confidence.

  • Two Gold-Standard Trials

    Two 12-week randomized, double-blind, placebo-controlled trials

  • Who Was Tested

    Trial 1: 113 women ages 45 to 55

    Trial 2: 210 women ages 45 to 60

  • What They Took

    One capsule of Oval's Estrobolome Complex™ each day for 90 days

  • The Results

    69% higher estrogen levels than placebo after 12 weeks

What is a gold-standard clinical trial?

A gold-standard clinical trial is a randomized, double-blind, placebo-controlled study—the most rigorous way to test whether a product truly works. Participants are randomly assigned to receive either the active product or a placebo, and neither they nor the researchers know who gets which until the study ends. This design eliminates bias and ensures reliable, scientific results.

About Us

Our mission is to help women navigate the hormonal changes of midlife with confidence and clarity.

Estrogen influences so much of how you feel—from your energy, mood, and focus to your sleep, skin, hair, libido, and weight. Yet when estrogen begins to decline, many women are left without clear guidance or reliable support.

That’s why we created the Estrogen Support Probiotic—a science-backed supplement designed to ease the physical and emotional ups and downs of perimenopause and menopause by sustaining estrogen naturally.

We’re committed to products that are grounded in clinical research, transparent in how they work, and focused on real physiological benefits, not vague promises or trends.

What matters most to us is helping you feel more confident, more in control, and more like you every day.

FAQs

Why Oval?

Oval is a daily probiotic designed to support your body’s own estrogen balance during perimenopause and menopause. Rather than adding hormones, it works through the gut microbiome to help your body maintain natural hormonal stability—supporting mood, metabolism, skin, hair, sex, sleep, and long-term health.

What Are The Benefits?

Oval supports steady estrogen levels. Benefits of maintaining estrogen as you age include:

Clearer Mind & Steadier Mood: Supports memory, focus, and emotional balance

Healthier Weight: Supports a leaner, more comfortable body and helps prevent midsection weight gain

Glowing Skin: Promotes firmer, smoother, more radiant skin

Thicker, Shinier Hair: Supports fuller, healthier-looking hair

Restful Sleep: Supports deeper sleep and stable nighttime temperature

Sexual Wellness: Increases comfort, natural lubrication, and sex drive

Stronger Bones & Heart: Supports long-term bone and cardiovascular health

Who is it for?

Oval is for women navigating hormonal changes in their 30s, 40s, and 50s+ who want to feel more like themselves again. It supports key areas commonly affected by estrogen changes, including mood, focus, metabolism, sleep, skin, hair, and libido. It may also be a good option for women who are not using hormone therapy.

Does it contain hormones?

No. Oval’s Estrogen Support Probiotic is completely non-hormonal. It doesn’t contain estrogen or alter your hormone production—it supports your body’s natural ability to recycle and balance its own estrogen.

Can I take it with hormone therapy (HRT/MHT)?

Yes. Oval is safe to take alongside HRT/MHT and can complement it. Many women use Oval before, during, or after hormone therapy to support gut health and healthy estrogen metabolism.

Is it safe to take every day?

Yes. Oval’s probiotic strains are clinically studied, well-tolerated, and safe for long-term daily use. Because it’s non-hormonal and microbiome-based, it supports both hormonal and digestive health naturally.

How Long Does It Take?

Hormone-related changes don’t happen overnight. Clinical studies showed results after 12 weeks of daily use, which is why we recommend giving your body a full three months to respond and settle into a new rhythm.

How does Oval work?

Oval supports a part of the gut microbiome called the estrobolome, the community of bacteria that help regulate and recycle estrogen. By restoring this natural process, Oval helps maintain steadier estrogen levels and smoother hormonal transitions while also supporting digestion, metabolism, and overall well-being.

What is the estrobolome?

The estrobolome (pronounced ESS-tro-bo-lome) is the group of gut bacteria that help regulate how estrogen is processed in the body. These bacteria produce enzymes that reactivate estrogen so it can be reabsorbed and reused instead of being lost. When the estrobolome becomes less active, as often happens during perimenopause and menopause, more estrogen is excreted, contributing to symptoms like hot flashes, mood changes, and fatigue. Supporting a healthy estrobolome helps your body maintain a more balanced hormonal environment naturally.

What is beta-glucuronidase?

Beta-glucuronidase (pronounced BAY-tuh gloo-kyoor-ON-ih-dase) is an enzyme made by certain gut bacteria that helps reactivate estrogen in the body. When estrogen is processed by the liver, it is often bound for excretion; beta-glucuronidase releases that bound estrogen, allowing it to be reabsorbed and recirculated naturally. This recycling process is one of the estrobolome’s key roles in maintaining hormonal balance.

Is Oval clinically studied?

Yes. The probiotic strains in Oval’s formula have been evaluated in two randomized, double-blind, placebo-controlled clinical trials with more than 300 women. Women taking the probiotic blend maintained healthier estrogen levels and experienced improvements in hot flashes, sleep, fatigue, and mood after 12 weeks of daily use.

Is it possible to quantify the effect of estrogen recycling?

Yes, indirectly. Researchers measure how efficiently the body recycles estrogen by looking at changes in circulating hormone levels, especially estradiol (E2), after interventions that influence the gut microbiome. In clinical studies, women taking Oval’s probiotic blend maintained 62% higher estradiol levels compared with placebo after 12 weeks, suggesting measurable support for natural estrogen recycling.

When will I start to feel a difference?

Every woman’s body is different, but many begin noticing changes, like better sleep, improved mood, or increased comfort, within 6 to 8 weeks. In clinical studies, measurable benefits were seen after 12 weeks of consistent use.

How do I take it?

Take one capsule daily with food or as part of your morning routine. The key is consistency—it works best when you take it every day.

What are the ingredients?

Each Capsule contains:

Oval Estrobolome Complex™ – a proprietary blend of three clinically studied probiotic strains (Lactiplantibacillus plantarum KABP051, Levilactobacillus brevis KABP052, and Pediococcus acidilactici KABP021) shown to support natural estrogen recycling and counter the symptoms of estrogen decline

Lactobacillus rhamnosus GG – a well-researched probiotic strain for women's health that reinforces gut-barrier integrity, reduces inflammation, and supports vaginal microbiome balance

Organic Acacia Fiber – a gentle prebiotic that nourishes beneficial gut bacteria and helps maintain microbiome stability

All ingredients are non-GMO, gluten-free, and suitable for daily use.

What makes Oval different?

Most menopause supplements focus on symptom relief using herbs or plant estrogens. Oval is rooted in microbiome science—it helps your body support its own estrogen naturally through the gut–hormone connection. It’s a smarter, more effective, and sustainable way to promote balance from within.

Can I take Oval with another probiotic?

You can, but it’s usually not needed. Oval’s formulation is comprehensive and specifically designed to target both gut and hormonal health at once.