My midsection feels less puffy and my digestion finally feels regular again.
Clinically Studied. Doctor Recommended.
The Estrogen Support Probiotic
Research has shown that the gut microbiome plays an essential role in women's hormonal health. Oval's Estrogen Support Probiotic boosts your body's natural hormone recycling power with clinically studied strains.
Research has shown that the gut microbiome plays an essential role in women's hormonal health. Oval's Estrogen Support Probiotic boosts your body's natural hormone recycling power with clinically studied strains.
Supports

How Oval Works
How Oval Works
How We Compare
Why We Built Oval
We built Oval to bring clarity and better solutions to women’s midlife health. We started with estrogen because it touches nearly every aspect of our wellbeing—from energy and mood to skin, hair, sleep, sex, and weight. Our mission is to deliver science-backed tools that help women navigate midlife with confidence and ease.
Why Oval?
Oval is a daily probiotic designed to support your body’s own estrogen balance during perimenopause and menopause. Rather than adding hormones, it works through the gut microbiome to help your body maintain natural hormonal stability—supporting mood, metabolism, skin, hair, sex, sleep, and long-term health.
What Are The Benefits?
Oval supports steady estrogen levels. Benefits of maintaining estrogen as you age include:
Clearer Mind & Steadier Mood: Supports memory, focus, and emotional balance
Healthier Weight: Supports a leaner, more comfortable body and helps prevent midsection weight gain
Glowing Skin: Promotes firmer, smoother, more radiant skin
Thicker, Shinier Hair: Supports fuller, healthier-looking hair
Restful Sleep: Supports deeper sleep and stable nighttime temperature
Sexual Wellness: Increases comfort, natural lubrication, and sex drive
Stronger Bones & Heart: Supports long-term bone and cardiovascular health
Who is it for?
Oval is made for women in their 30s, 40s, 50s, and beyond who want to support their mood, mind, metabolism, skin, hair, sex drive, sleep, and long-term health during perimenopause and menopause. It’s also a good choice for women who cannot or prefer not to use hormone therapy.
Does it contain hormones?
No. Oval’s Estrogen Support Probiotic is completely non-hormonal. It doesn’t contain estrogen or alter your hormone production—it supports your body’s natural ability to recycle and balance its own estrogen.
Can I take it with hormone therapy (HRT/MHT)?
Yes. Oval is safe to take alongside HRT/MHT and can complement it. Many women use Oval before, during, or after hormone therapy to support gut health and healthy estrogen metabolism.
Is it safe to take every day?
Yes. Oval’s probiotic strains are clinically studied, well-tolerated, and safe for long-term daily use. Because it’s non-hormonal and microbiome-based, it supports both hormonal and digestive health naturally.
Why is Oval Subscription-Only?
Hormonal balance takes time and consistency. Oval works best when taken daily, so a subscription ensures you never miss a dose.
Why a 3-month supply?
Clinical studies showed measurable results after 12 weeks of use. A 90-day plan gives your body the time it needs to restore estrogen balance naturally.
How does Oval work?
Oval supports a part of the gut microbiome called the estrobolome, the community of bacteria that help regulate and recycle estrogen. By restoring this natural process, Oval helps maintain steadier estrogen levels and smoother hormonal transitions while also supporting digestion, metabolism, and overall well-being.
What is the estrobolome?
The estrobolome (pronounced ESS-tro-bo-lome) is the group of gut bacteria that help regulate how estrogen is processed in the body. These bacteria produce enzymes that reactivate estrogen so it can be reabsorbed and reused instead of being lost. When the estrobolome becomes less active, as often happens during perimenopause and menopause, more estrogen is excreted, contributing to symptoms like hot flashes, mood changes, and fatigue. Supporting a healthy estrobolome helps your body maintain a more balanced hormonal environment naturally.
What is beta-glucuronidase?
Beta-glucuronidase (pronounced BAY-tuh gloo-kyoor-ON-ih-dase) is an enzyme made by certain gut bacteria that helps reactivate estrogen in the body. When estrogen is processed by the liver, it is often bound for excretion; beta-glucuronidase releases that bound estrogen, allowing it to be reabsorbed and recirculated naturally. This recycling process is one of the estrobolome’s key roles in maintaining hormonal balance.
Is Oval clinically studied?
Yes. The probiotic strains in Oval’s formula have been evaluated in two randomized, double-blind, placebo-controlled clinical trials with more than 300 women. Women taking the probiotic blend maintained healthier estrogen levels and experienced improvements in hot flashes, sleep, fatigue, and mood after 12 weeks of daily use.
Is it possible to quantify the effect of estrogen recycling?
Yes, indirectly. Researchers measure how efficiently the body recycles estrogen by looking at changes in circulating hormone levels, especially estradiol (E2), after interventions that influence the gut microbiome. In clinical studies, women taking Oval’s probiotic blend maintained 62% higher estradiol levels compared with placebo after 12 weeks, suggesting measurable support for natural estrogen recycling.
When will I start to feel a difference?
Every woman’s body is different, but many begin noticing changes, like better sleep, improved mood, or increased comfort, within 6 to 8 weeks. In clinical studies, measurable benefits were seen after 12 weeks of consistent use.
How do I take it?
Take one capsule daily with food or as part of your morning routine. The key is consistency—it works best when you take it every day.
What are the ingredients?
Each Capsule contains:
Oval Estrobolome Complex™ – a proprietary blend of three clinically studied probiotic strains (Lactiplantibacillus plantarum KABP051, Levilactobacillus brevis KABP052, and Pediococcus acidilactici KABP021) shown to support natural estrogen recycling and counter the symptoms of estrogen decline
Lactobacillus rhamnosus GG – a well-researched probiotic strain for women's health that reinforces gut-barrier integrity, reduces inflammation, and supports vaginal microbiome balance
Organic Acacia Fiber – a gentle prebiotic that nourishes beneficial gut bacteria and helps maintain microbiome stability
All ingredients are non-GMO, gluten-free, and suitable for daily use.
What makes Oval different?
Most menopause supplements focus on symptom relief using herbs or plant estrogens. Oval is rooted in microbiome science—it helps your body support its own estrogen naturally through the gut–hormone connection. It’s a smarter, more effective, and sustainable way to promote balance from within.
Can I take Oval with another probiotic?
You can, but it’s usually not needed. Oval’s formulation is comprehensive and specifically designed to target both gut and hormonal health at once.